Complete Genome Sequence of Human Coronavirus OC43 Isolated from Mexico B. T. Taboada,a P. Isa,a M. A. Espinoza,a F. E. Aponte,a M. A. Arias-Ortiz,b J. Monge-Martínez,b R. Rodríguez-Vázquez,b F. Díaz-Hernández,b F. Zárate-Vidal,b R. M. Wong-Chew,c V. Firo-Reyes,d C. N. del Río-Almendárez,e J. Gaitán-Meza,f A. Villaseñor-Sierra,g G. Martínez-Aguilar,h M. García-Borjas,h D. E. Noyola,a L. F. Pérez-Gónzalez,j S. López,a J. I. Santos-Preciado,c C. F. Ariasa Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, Méxicoa; Colegio de Pediatría del Estado de Veracruz, Veracruz, Méxicob; Facultad de Medicina, Universidad Nacional Autónoma de México, México D.F., Méxicoc; Hospital General de México, México D.F., Méxicod; Hospital Pediátirco de Coyoacán, México D.F., Méxicoe; Nuevo Hospital Civil de Guadalajara “Dr. Juan I. Menchaca,” Guadalajara, Jalisco, Méxicof; Centro de Investigación Biomédica de Occidente, IMSS, Guadalajara, Jalisco, Méxicog; Hospital General de Durango, Durango, Méxicoh; Universidad Autónoma de San Luis Potosí, San Luis Potosí, Méxicoi; Hospital Central “Dr. Ignacio Morones Prieto,” San Luis Potosí, Méxicoj We report the complete genome sequence of the first Mexican human coronavirus (HCoV) OC43, obtained by new-generation sequencing and a metagenomic approach, isolated from a child hospitalized with pneumonia. The genome is closely related to the other OC43 genome sequences available, ranging from 99.8% to 98.2% nucleotide sequence identity. Received 20 September 2016 Accepted 22 September 2016 Published 10 November 2016 Citation Taboada BT, Isa P, Espinoza MA, Aponte FE, Arias-Ortiz MA, Monge-Martínez J, Rodríguez-Vázquez R, Díaz-Hernández F, Zárate-Vidal F, Wong-Chew RM, Firo-Reyes V, del Río-Almendárez CN, Gaitán-Meza J, Villaseñor-Sierra A, Martínez-Aguilar G, García-Borjas M, Noyola DE, Pérez-Gónzalez LF, López S, Santos-Preciado JI, Arias CF. 2016. Complete genome sequence of human coronavirus OC43 isolated from Mexico. Genome Announc 4(6):e01256-16. doi:10.1128/genomeA.01256-16. Copyright © 2016 Taboada et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license. Address correspondence to B. T. Taboada,