This article is protected by copyright. All rights reserved 1 Research Article Interpatient Mutational Spectrum of Human Coronavirus-OC43 Revealed by Illumina Sequencing† Geoffrey J. Gorsea,b*, Gira B. Patela,b, and Xiaofeng Fanc a VA St. Louis Health Care System, St. Louis, MO, USA b Division of Infectious Diseases, Allergy and Immunology, Saint Louis University School of Medicine, St. Louis, MO, USA c Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, St. Louis, MO, USA * Corresponding Author: Geoffrey J. Gorse, MD Division of Infectious Diseases, Allergy and Immunology, Saint Louis University School of Medicine 1100 South Grand Blvd. (DRC 8th Floor) Saint Louis, MO, USA Telephone: 314-977-5500 Fax: 314-771-3816 E-Mail Address: