Personalize your musculoskeletal models based on medical image data PAVEL GALIBAROV, PHD ANYBODY TECHNOLOGY Month Xrd201X Outline • Motivation for subject-specific modeling • Individualization principles and techniques • Anthropometric scaling • Individualization of body parts • Available tools • Code examples: • Full bone morphing • Bone morphing based on partially Pavel Galibarov available surface information (Presenter) • MoCap model with a subject-specific bone • Conclusion remarks Motivation: mass vs. personal products • Mass products • Computational models reduce costs • Target as many customers as possible • Allow virtual testing on a wide range of subjects • Vehicle interior/exterior • Workspace • Virtually cost free ergonomic and other analyses • Mobile device • Design based on anthropometric databases • Ethically sound product development • ANSUR • Shorter time-to-market • CAESAR • NHANES • etc. • Make product that are ‘personal’, but mass produced • Personal products • Best function for an individual as a selling point • Example: Shoe-insoles, medical devices, etc. Motivation: Ergonomic design • Seat and steering wheel adjustment mechanisms • Previous webcast: • Modeling Of Population Ergonomics With AnyBody • www.youtube.com/anybodytech • 16.000 subject-specific musculoskeletal models • Cross-correlated bone dimensions Motivation: Anatomic products • Linear scaling is simple – problem solved? • Not completely… • same bone length • different shape • different inner/outer cortex proportions • Muscle attachment configuration changes • Leads to different muscle activation patterns • Different joint loading Motivation: Anatomic products “SOMA (Stryker Orthopaedics Modeling and Analytics system), is a proprietary population-based design environment” http://www.stryker.com/ AxSOS 3 Plating System Motivation: Anatomic products Materialise ADaM™ for Population Analysis www.djoglobal.com/products/ djo-surgical/taperfill-hip-system biomedial.materialise.com ”Virtual population analysis improves orthopedic implant design” S. Kolk, M. Lawrenchuk, Orthopedic Design and Technology Magazine Motivation: Multiscale modeling • Consistent geometries in FEA and musculoskeletal models • Ensures quality of the muscular and joint reaction force transfer • Required for high level of precision to address such questions as, for example, bone remodeling Courtesy of Prof. Sebastian Dendorfer, OTH Regensburg, Germany Presented previously workflow Motivation: Anatomic accuracy • (Purple) Lower extremity bones from MRI • Personalized and registered AnyBody model • TLEMsafe project youtube.com/anybodytech