This textbook for instruction in biomedical research ethics can also                  serve as a valuable reference for professionals in the field of bioethics. The 149                  cases included in the book are grouped in nine chapters, each of which covers a key                  area of debate in the field. Some of the case studies are classics, including the                  famous cases of the Tuskegee Syphilis Study (in which subjects with syphilis were                  not given treatment) and the Willowbrook hepatitis studies (in which                  institutionalized subjects were intentionally exposed to hepatitis). Others focus on                  such current issues as human embryonic stem cell research, cloning by somatic                  nuclear transfer, and the design and function of institutional review boards. Each                  chapter begins with a brief introduction that places the issues raised in context;                  this is followed by a number of cases (each of which is no more than a few pages).                  Study questions meant to encourage further discussion follow each case.After an                  introductory discussion of the history and tenets of ethics in medical research, the                  book's chapters cover the topics of oversight and study design; informed consent;                  the selection of subjects; conflicts of interest; the social effects of research;                  embryos, fetuses, and children; genetic research; the use of animals; and authorship                  and publication. Following these chapters are appendixes with the texts of the                  Nuremburg Code and the World Declaration of Geneva, two key documents in the                  establishment of bioethical standards for research. Also included are a glossary, a                  table of cases by general category, and an alphabetical listing of cases.

Case Studies in Biomedical Research Ethics PDF

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