This book is the first of its kind that focuses on the chemistry and biology  of ellagitannins, a special class of naturally occurring polyphenols which  have so far not received the attention they deserve. These polyphenolic  substances are found in many plants, including numerous food sources. They not  only exhibit unique structural features that fascinate most chemists who are  aware of their existence, but also express remarkable biological activities  that have yet to attract the interest of the pharmaceutical industry. This is  surprising because ellagitannins have been identified as active principles in  traditional Chinese medicines.    The principal aim of this book is to set the record straight. Most, if not  all, worldwide experts in each aspect of the chemistry and biology of this  underestimated class of natural products have contributed to this book. It  covers topics such as their structural determination and natural occurrence;  the most up-to-date knowledge of their biosynthesis; the current state of the  art of their total chemical synthesis; their main physicochemical properties  and principal biological activities; their presence in food and beverages; and  their related health effects. All together, nine chapters compose this book  whose content is placed into historical perspective in a yet inspiring preface  written by one of the pioneers in modern polyphenol research, Professor Edwin  Haslam. This book will be useful not only to scientists involved in natural  product research, but also to lecturers and their students as a source of key  references and/or a textbook.    Contents:  Ellagitannins Renewed the Concept of Tannins; Structural Diversity  and Antimicrobial Activities of Ellagitannins; Biosynthesis of Ellagitannins:  Old Ideas and New Solutions; Physicochemical Properties and Biomimetic  Reactions of Ellagitannins; Strategies for the Synthesis of Ellagitannins;  Immunomodulatory Ellagitannin Chemistry; Bioavailability and Metabolism of  Ellagic Acid and Ellagitannins; Sources and Health Effects of Dietary  Ellagitannins; C-Glycosidic Ellagitannins and Their Influence on Wine  Chemistry.

Chemistry and Biology of Ellagitannins: An Underestimated Class of Bioactive Plant Polyphenois PDF

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