The new edition of this atlas integrates all significant advances made in the past 15 yearsin molecular pathology, tumor virology, and genetics of cervical cancer. It emphasizesthe importance of these advances in facilitating its pathological diagnosis and in optimizingclinical management and prognosis.A new chapter on immunohistochemistryhas been added, which includes refined detection methods, e.g., the overexpression ofp16INK4a as a molecular marker in the early differential diagnosis of premalignant lesions.The section on etiology and pathogenesis in human papillomavirus-inducedneoplasia has been incorporated to represent new insights into the sequences of cellularand nuclear deregulation at the molecular level.All chapters have been revised to includethe newest advances and relevant experiences in how to interpret and managecervical disease; they are supported by the addition of 35 new microphotographic illustrations.The tumor nomenclature is adapted to the latest edition of the WHO classification;the morphology code of the international classification of diseases for oncology(ICD-O) has been added.We have also updated the list of references by adding recentrelevant publications.Again, the staff of Springer-Verlag deserve our thanks for their patience and skill inpreparing the manuscript and in reproducing the microphotographs.

Color atlas of histopathology of the cervix uteri. PDF

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