Building upon the foundation of basics discussed in the previous edition, the Second Edition provides a more in-depth look at the latest methods and technologies of advanced drug screening, an essential function of drug discovery.     With extensively updated content and 21 new chapters, this text examines:          quality and efficiency of drug target validation and potential drug compound selection  reducing assay costs and improvement in assay technology  data quality improvement  trends in drug discovery  how drug screening can minimize adverse drug effects  recent advancements, including: high content screening; protein-protein interactions; high-throughput crystallization; lead optimization; chemoinformatics and microfluidics technologies; target validation by genomics, proteomics, and siRNA; structure-based drug design; automation; and medicinal chemistry

Handbook of Drug Screening, 2nd Edition (Drugs and the Pharmaceutical Sciences) PDF

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