Functional genomics--the deconstruction of the genome to determine the                  biological function of genes and gene interactions--is one of the most fruitful new                  areas of biology. The growing use of DNA microarrays allows researchers to assess                  the expression of tens of thousands of genes at a time. This quantitative change has                  led to qualitative progress in our ability to understand regulatory processes at the                  cellular level.This book provides a systematic introduction to the use of DNA                  microarrays as an investigative tool for functional genomics. The presentation is                  appropriate for readers from biology or bioinformatics. After presenting a framework                  for the design of microarray-driven functional genomics experiments, the book                  discusses the foundations for analyzing microarray data sets, genomic data-mining,                  the creation of standardized nomenclature and data models, clinical applications of                  functional genomics research, and the future of functional genomics.

Microarrays for an Integrative Genomics, 3rd edition (Computational Molecular Biology) PDF

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