RCSB  Protein  Data  Bank   Advisory  Committee  Meeting   October  30th  2014 Overview   Stephen  K.  Burley Leadership  Transition   !  Stephen  K.  Burley,  Director   !  Overall  direction  of  RCSB  PDB  as  of  July  2014   !  Formally  responsible  for  Rutgers  and  UCSD   !  Helen  M.  Berman,  Associate  Director   !  External  Partnerships  related  to  hybrid  or  integrative   structure  determination  methods   !  Unchanged  roles  in  SBKB/NDB/EMDataBank   !  Philip  E.  Bourne–exited  early  in  2014   !  Associate  Director  for  Data  Science,  NIH   2 Advisory  Groups   Advisory  Committees   !  RCSB  PDB  AC:  Cynthia  Wolberger  (Johns  Hopkins)   !  wwPDB  AC:  Soichi  Wakatsuki  (Stanford/SLAC)   Working  Group   !  PDBx/mmCIF:  Paul  Adams  (LBL)   wwPDB  Task  Forces  and  Workshops   !  X-­‐ray  Validation:  Randy  Read  (Univ  of  Cambridge)     !  3DEM  Validation:  Richard  Henderson  (MRC-­‐LMB),     Andrej  Sali  (UC  San  Francisco)   !  NMR  Validation:  Gaetano  Montelione  (Rutgers),   Michael  Nilges  (Institut  Pasteur)   !  Small-­‐Angle  Scattering:  Jill  Trewhella  (Univ  Sydney)   !  Hybrid  Methods:  Andrej  Sali  (UC  San  Francisco),     Torsten  Schwede  (Univ  Basel),  Jill  Trewhella  (Univ  Sydney)   3 2014  Strategic  Planning   !  July  meeting  with  Leadership  Team  to  draft     Core  Values,  Vision,  and  Mission   !  Reviewed  broadly  "  additional  re^inements   !  Informed  drafting  of  project,     team,  and  individual  objectives   4 Vision  &  Mission   5 Core  Values   6 Response  to  2013  Recommendations   AC:   Integration  of  KB  and  RCSB  PDB   Response:   Deferred  until  the  fate  of  KB  determined   AC:   Review  PDB-­‐101  materials  for  effectiveness,  and  outreach  efforts   for  cost  effectiveness   Response:   Fall  2014  survey  informing  redesign  efforts   AC:   Development  of  online  courses  with  external  funding   Response:   Submitted  proposal  under  review   AC:   Major  redesign  of  rcsb.org  website   Response:   In  progress  (Phase  1);  Addressed  in  Data  Out     AC:   Suppression  of  structure  title  in  unreleased  entries   Response:   Implemented  as  explicit  depositor  option  in  the  new  system   7 PDB  Depositors   Growing  Number  of         ~850  new  entries/month   PDB  Depositions   PDB  User  Access    2  0  13  FTP  and  RSYNC  Download  Traf^ic   433  million  downloads     2013:  10566  depositions   49%  increase  in  the  number  of   global  depositions  since  2008   RCSB  PDB:  312  million   PDBe:  81  million   PDBj:  40  million       8 Ensuring  Data  Are  Freely  and  Globally  Available   !  Partners   !  RCSB  PDB  (Research  Collaboratory  for  Structural   Bioinformatics,  Rutgers/UCSD)   !  PDBj  (Osaka  University)   !  PDBe  (EMBL-­‐EBI)   !  BioMagResBank  (University  of  Wisconsin,  Madison)   !  Collaborate  on  the  guiding  policies  for  uni^ied  data   processing  (Data  In)  and  archive  management   !  Each  partner  website  offers  diverse  services  and   views  of  the  data  (Data  Out)       9