Complete remissions and survival times of tumor patients are increasing steadily - and so is the risk of developing therapy-associated secondary malignancy. At the same time, we face the growing diagnostic and therapeutic problem of tumorigenesis during posttransplantation immunosuppressive therapy. The theoretical section delves into the various causes of tumorigenesis, with special chapters on secondary chemo- and/or radiotherapy-induced tumorigenesis and neoplasia occurring during posttransplantation immunosuppressive therapy. The risk of individual cytostatic agents causing secondary malignoma is covered, as are the functions and dysfunctions of immunosurveillance. The immune system's methods of recognizing tumors are also examined, and specific information on the role of herpesviruses in organ transplantation is included.

Secondary Neoplasias Following Chemotherapy, Radiotherapy and Immunosuppression: Secondary Neoplasias After Organ Transplants and Radiotherapy (Contributions to Oncology, 55)

Secondary Neoplasias Following Chemotherapy, Radiotherapy and Immunosuppression: Secondary Neoplasias After Organ Transplants and Radiotherapy (Contributions to Oncology, 55) PDF

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