MMAANNAAGGEEMMEENNTT OOFF MMUULLTTIIPPLLEE SSCCLLEERROOSSIISS:: AAPPIITTHHEERRAAPPYY IN THE NAME OF GOD The Effect of Bee Venom on Rheumatoid Arthritis Patients Ahmed G. Hegazi1 Maha M. Saber2, Eitedal Daoud2, Aliaa al Gendy2, Khaled G. Abdel-Wahhab3 and Eman Abd el-Rahman 4 National Research Centre, Dokki, Giza, Egypt The Effect of Bee Venom on Rheumatoid Arthritis Patients (cid:1) Special thanks to Scientific Committee of the 44th IInntteerrnnaattiioonnaall CCoonnffeerreennccee aanndd Immunology Exhibition on September 28-30, 2015 Houston, Texas, USA The Effect of Bee Venom on Rheumatoid Arthritis Patients What Apiacupuncture can do for arthritis? Apitherapy (cid:1) One of the major peptides in bee venom, called Melittin, is used to treat inflammation in sufferers ooff RRhheeuummaattooiidd AArrtthhrriittiiss and Multiple Sclerosis. (cid:1) Melittin blocks the expression of inflammatory genes, thus reducing swelling and pain. (cid:1) It is administered by direct insect sting, or intramuscular injections. What type of conditions is Bee venom used to treat? (cid:1) Bee venom simulates the release of cortisone (cortisol) (cid:1) It is effective in the treatment of rrhheeuummaattiicc ddiisseeaasseess,, eessppeecciiaallllyy arthritis and multiple sclerosis (MS). (cid:1) It can be applied directly or by intradermal injections. What type of conditions is Bee venom used to treat? (cid:1) ointment - Apireven – (cid:1) liniment (cid:1)(cid:1) bbootthh hhaavvee bbeeeenn uusseedd ssuucccceessssffuullllyy iinn sseevveerraall ccaasseess ooff rrhheeuummaattooiidd polyarthritis. (cid:1) The results have shown an important reduction in muscular pain, sciatic pain, nerve pain, neuromialgias and intercostal and bbrroonncchhiiaall nneerrvvee ppaaiinn.. Applying the venom topically can provide (cid:1) a long-lasting effect (cid:1) and can offer significant benefits in arthritic and rheumatic conditions. Bee venom causes •local pain, •redness, • swelling in people who are not allergic.